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A webinar hosted by CRASH-4 on the benefits of intramuscular TXA administration
On 10th September 2024, the CRASH-4 trial’s Chief Investigator delivered a pivotal webinar on the administration of intramuscular tranexamic acid (IM-TXA) in emergency medicine. The session highlighted key lessons and recommendations drawn from the Manchester Arena Bombing inquiry, which emphasized the critical role of timely IM-TXA administration in trauma care, especially in mass casualty situations.
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A patient’s perspective in CRASH-4
We are incredibly fortunate to hear directly from a CRASH-4 trial participant as they share their personal journey of being enrolled in the study. In this video, they recount their experience, highlighting the meticulous care and support they received from the dedicated team at Dorset County Hospital. Their story offers a unique and heartfelt perspective
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CRASH-4 Recommended for NIHR Funding!
After having recruited over 700 CRASH-4 participants, we are delighted to announce that CRASH-4 has been recommended for funding by the NIHR-HTA programme! Whatever your involvement has been in the trial up to this point, it wouldn’t have been possible to reach this stage without you so thank you! This means that we can now
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Injured Women Half as Likely as Men to Receive Tranexamic Acid
New research has found that female trauma patients are half as likely as men to receive tranexamic acid – even though the treatment is equally effective regardless of sex. This highlights the urgent need to improve equity in trauma care. Read the full article here.
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Cost-effectiveness of TXA for older adults experiencing mild traumatic brain injury
Mild traumatic brain injury in older adults is a huge problem in the UK. Finding out if tranexamic acid improves outcomes is well worth the cost according to recent economic modelling. The CRASH-4 trial will answer this important question. Read the full article here.
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Innovative Research Car Initiative at South Central Ambulance Service
A pioneering initiative at South Central Ambulance Service (SCAS) is seeing research paramedics attend potentially eligible CRASH-4 patients in dedicated research cars. We know TXA is more effective the earlier it is given, and the research cars allow eligible patients to be attended rapidly and recruited as quickly as possible. Click here to read the
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A £2 jab that can save thousands of lives but 95% of those eligible aren’t given it
TXA could save a third of people who are suffering major blood loss. Read more below: https://www.dailymail.co.uk/health/article-10224629/2-jab-save-thousands-trauma-patients-bleeding-death.html
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Potential facilitators to prehospital TXA administration proposed in new research
New research findings show a potential facilitator to TXA Administration is through different routes, in new research on barriers of prehospital TXA use published by researchers at the University of West England, Bristol. ‘Our findings suggest several potential facilitators to TXA administration, including different administration routes, further training on the benefits of TXA and an
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First patient randomised!
Congratulations to St George’s Hospital for recruiting the first patient to the CRASH-4 Trial! Well done to PI Heather Jarman and the team to be the first site to recruit!
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