On 10th September 2024, the CRASH-4 trial’s Chief Investigator delivered a pivotal webinar on the administration of intramuscular tranexamic acid (IM-TXA) in emergency medicine. The session highlighted key lessons and recommendations drawn from the Manchester Arena Bombing inquiry, which emphasized the critical role of timely IM-TXA administration in trauma care, especially in mass casualty situations.

During the webinar, the Chief Investigator provided detailed insights into the benefits of integrating IM-TXA into emergency protocols, particularly for patients with life-threatening bleeding where intravenous access may be delayed or not feasible. The discussion underscored the potential of IM-TXA to save lives in pre-hospital settings, including its practical application by paramedics, first responders, and military personnel in austere environments.

Participants were also able to engage directly with the CRASH-4 team, raising important questions on the efficacy, safety, and best practices for using IM-TXA. These questions, and the responses provided, are available in the recorded session, offering a valuable resource for healthcare professionals seeking to stay at the forefront of trauma care advancements.

If you missed the session, don’t worry! The next CRASH-4 webinar will be held on 23rd October 2024, where the discussion will continue with a deeper dive into the latest research findings and clinical experiences related to IM-TXA. To receive the webinar link, please email crash4@lshtm.ac.uk.